What is Low Dose Naltrexone (LDN)?
Naltrexone is a drug introduced in 1984 to counter the effects of opioid drug overdose, with typical dosages ranging from 50-100mg for these purposes. In the 1990s, much lower doses (1.5-4.5mg) began to be used for other purposes, such as supporting the immune system and addressing inflammatory and neurological conditions.
Ready to Get Started?
At Boudreaux’s New Drug Store, we collaborate with patients and providers to solve medication challenges.
Conditions Commonly Addressed with Low Dose Naltrexone (LDN)
Many providers worldwide report positive responses in patients using LDN for various conditions. Some commonly addressed conditions include:
- Chronic Fatigue, Fibromyalgia
- Irritable Bowel Syndrome (IBS), Crohn’s Disease, Ulcerative Colitis
- Auto-immune Thyroiditis (Hashimoto’s and Graves)
- HIV/AIDS
- Chronic Pain Syndromes
- Autism
- Psoriasis, Eczema
- Arthritis
- Inflammatory Diseases
- Depression
- Restless Leg Syndrome
- Lupus
How Does Low-Dose Naltrexone Work?
LDN therapy is thought to involve several mechanisms of action that may work together to support patient health. These include:
Increased Endorphin Secretion
Endorphins are naturally occurring substances that help relieve pain, create feelings of happiness, and reduce inflammation.
Opioid Growth Factor Release
This factor may help reduce inflammation, support immune responses, and affect cell growth.
Reduced Inflammatory Immune Cell Signaling
By affecting cells that signal the immune system, LDN may help modulate immune responses and inflammation.
Calming Glial Cells in the Nervous System
Glial cells play a significant role in the immune system and nervous system health, and calming them may support nerve function and reduce inflammation.
Increased Dopamine Levels
Dopamine is a neurotransmitter that influences mood, energy levels, and cognitive functions
The response time to LDN therapy can vary. Some individuals notice improvements within the first two months, though a period of up to eight months is often recommended to observe maximum benefits.
LDN is generally well-tolerated, but some individuals may experience side effects such as vivid dreams in the first few days. Occasionally, headaches or body aches may occur. It’s also important to monitor thyroid function, as LDN may affect thyroid medication efficacy.
Several factors may influence the development of auto-immune and inflammatory conditions. The pharmacists at Boudreaux’s New Drug Store are available to offer advice on supplements, nutrition, and lifestyle choices that may complement LDN therapy.
For more information about LDN and how it may fit into your health management plan, reach out to Boudreaux’s New Drug Store. Our pharmacists are here to support your unique needs.
